General description

Anti-CD20 (B-cell Pan) reacts with a membrane antigen that is present in B-cells. This antibody recognizes Reed-Sternberg cells, predominant in Hodgkin’;s disease, in a minority of cases. Since no staining of histiocytes or plasma cells has been observed and CD20 has not been detected in T-cell malignancies, it is a very strong marker of B-cell lymphomas. Anti-CD20 does not cross-react with non-hematopoetic neoplasms.

Legal Information

Cell Marque is a trademark of Sigma-Aldrich Co. LLC

Linkage

CD20 Positive Control Slides, Product No. 120S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Other Notes

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Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and ﹤0.1% Sodium Azide

Preparation Note

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Quality